The explosive growth of genetic seq

The explosive growth of genetic sequence information
has offered us comprehensive collections of the protein
sequences found in many living organisms.Most of these
are not experimentally characterized. Although half of
the proteins that are encoded in sequenced eukaryotic
genomes have computationally recognized homology to
at least one well-characterized domain1,2, functional
interpretation of these matches is fraught with difficulty.
Functional changes over evolutionary time3,4 and database
errors5 confound reliable computational prediction
of the precise roles of newly discovered genes.Even proteins
with recognized domains are often scattered with
regions of unmatched sequence. So, most of the residues
in putative gene products lack any computational annotation,
and there exists no general experimental approach
to directly ascertain their molecular role.

結果 (中文) 3:

基因序列信息的爆炸性增长为我们提供了全面的蛋白质收集在许多生物体中发现的序列。不实验的特点。虽然一半编码真核生物的蛋白质基因组具有计算上的同源性至少有一个很好的特点domain1,2，功能对这些比赛的解释充满困难。在进化的time3,4和数据库功能的变化错误11连动错误5混淆可靠的计算预测新发现的基因甚至蛋白质的精确角色与公认的领域往往分散非匹配序列区域。所以，大部分的残留物在假定的基因产品缺乏任何计算注释，并没有普遍的实验方法直接确定其分子作用。