With the optimized component, the AuAg3.2 NSs show superior SA and MA forORR (1.36 mA cm−2, 1.26 A mgAu−1), EG oxidation (8.2 mAcm−2, 7.58 A mgAu−1), and glucose oxidation (1.59 mA cm−2, 1.48 A mgAu−1) compared to the commercial Pt/C benchmark and also exhibit the highest catalytic activities among Au−Ag systems reported to date.