Pseudoangiomatous stromal hyperplas

Pseudoangiomatous stromal hyperplasia (PASH) is a benign disease of the breast characterized by a complex network of slitlike spaces lined by slender spindle cells within a background of stromal hyperplasia [1] (Figs. 1C and 1D). The etiologic factors of PASH are unknown, but most investigators think that it represents a proliferative response of myofibroblasts, probably to hormonal stimuli [1–3]. The purpose of the present study was to describe the imaging appearance of PASH with pathologic and clinical correlation.
We performed a retrospective review of our institution's surgical pathology database for the histologic diagnosis of PASH from January 1998 through December 2006. Cases without available imaging results or in which PASH was an incidental finding were excluded. We identified 57 cases, all in female subjects (mean age, 48 years; range, 9–76 years), for which PASH was the sole or dominant pathologic finding and for which imaging results were available. Diagnosis was obtained for 48 patients from percutaneous biopsies: two en bloc 12-mm radiofrequency biopsies, 12 biopsies with vacuum-assisted devices (9- and 11-gauge), and 34 core needle biopsies (14-gauge needle, 29 biopsies; 16-gauge needle, three biopsies; and 18-gauge needle, two biopsies). Nine cases were identified from excisional biopsies.

結果 (繁體中文) 2:

Pseudoangiomatous間質增生（PASH）是一種特徵為間質增生[1]（圖1C和1D）的背景內用細長的梭形細胞內襯狹縫狀的空間的複雜網絡乳腺的良性疾病。PASH的病因是未知的，但多數研究者認為它代表肌成纖維細胞的增殖反應，可能是荷爾蒙的刺激[1-3]。本研究的目的是描述PASH的影像學表現與病理和臨床相關性。
我們到十二月執行我們機構的手術病理數據庫PASH從1998年1月組織學診斷的回顧性分析2006例無可用的成像效果還是其中PASH是一個偶然的發現被排除在外。我們確定57案件，在所有女性受試者（平均年齡48歲，範圍9-76歲），為此，PASH是唯一或主要的病理發現和其成像效果可用。對48例患者得到診斷從經皮活檢：二整塊12毫米射頻活組織檢查，12活檢與真空輔助設備（9-和11-表壓），和34空芯針穿刺活檢（14號針頭，29活組織檢查; 16 -Gauge針，三活組織檢查;和18號針頭，二活檢）。九例被確定從活檢切除。