No significant differences were seen in fractional (day 1–3 geometric mean: 11・8% [7・1, 19・4] once daily vs 13・1% [8・2, 20・7] twice daily; p=0・33) or total iron absorption (day 1–3: 44・3 mg [29・4, 66・7] once daily vs 49・4 [35・2, 69・4] twice daily; p=0・33) between the two dosing regimens.