The recovery rate and RSD for each PAE at different concentrations are listed in Table 3. No matrix effect was found (Figure S5) and the spiked recoveries were76.26–107.76%, the RSD range was from 1.78 to 10.84% (intra-day precision) and 3.33 to12.10% (inter-day precision). The results indicate the method fully meets the demands for the determination of the 22 PAEs in food packing materials.