Expression Patterns TAp63 and ΔNp63 exhibit rather
different patterns of expression restricted to only a few
physiological tissues. During adulthood, ΔNp63 isoforms
(predominantly ΔNp63α) are expressed abundantly in
basal epithelial cells, such as the basal layer of the skin,
the myoepithelial cells of the breast, the basal cells
of the prostate [31], and thymic epithelial cells.During mouse development, ΔNp63α transcripts can be
detected in the simple ectoderm at embryonic day 11
(E11), prior to stratification, and by E17 ΔNp63α can
be strongly detected in the basal layer, but not in more
superficial layers. On the other hand, TAp63 isoforms
are expressed at significant levels only in the
female germline