A study of people with schizophrenia found that their gray matter network was characterized
by an increased physical distance between connected nodes, suggestive of inefficient wiring,
and attenuated hierarchical organization of heteromodal cortex, which might be indicative of
abnormal neurodevelopment [14]. In Alzheimer’s disease, gray matter networks have been
associated with changes in the degree distribution associated with a more lattice-like network
which is highly sensitive to computationally simulated lesions to the hub nodes [15,44]