The overall follow-up of the 40 patients treated was 7–69 months (mean 35 months). Helical CT follow-up demonstrated complete necrosis (absence of enhancing tissue during arterial-phase acquisition) in 28 of 40 cases (70%) (Fig. 4). A partial necrotizing effect was noted in the remaining 12 large HCCs (patients), all being larger than 50
mm in diameter. In these 12 subjects a 5–30% area of residual viable enhancing tissue was noted and complete necrosis was obtained only after a second treatment session (11 cases) or a third treatment session (1 case). Ultimately, complete (100%) necrosis was obtained in all our patients
with one to three treatment sessions (mean 1.3sessions per patient) (Table 1).