More recently, a screen of 88 antic

More recently, a screen of 88 anticancer drugs from the NCI FDA-approved oncology drug set confirmed the hair cell toxicity of four known hair cell toxins, further validating the platform’s specificity.


In addition, we confirmed the hair cell toxicity of four antineoplastic drugs suspected to be potential ototoxins and identified five additional anticancer therapeutics as potential ototoxins [39].

結果 (繁體中文) 1:

最近，88 抗癌藥物從 NCI FDA 批准腫瘤藥物組螢幕確認四個已知的毛細胞毒素，進一步驗證平臺的特異性的毛細胞毒性。此外，我們證實疑為潛在的 ototoxins 的四類抗腫瘤藥物的毛細胞毒性和五個額外的抗癌療法列為潛在 ototoxins [39]。

結果 (繁體中文) 2:

最近，88抗癌藥物從NCI FDA批准的腫瘤學藥物組的畫面確認的四種已知毛細胞毒素毛細胞毒性，進一步驗證平台的特異性。另外，我們證實了四個抗腫瘤藥懷疑毛細胞毒性是潛在的ototoxins，並確定了五個其他抗癌療法的潛在ototoxins [39]。

結果 (繁體中文) 3:

最近，來自NCI的FDA準予的腫瘤藥物證實已知的四毛細胞毒素的毛細胞毒性抗癌藥物篩選88，進一步驗證了該平臺的特异性。


此外，我們確認涉嫌四抗腫瘤藥物的毛細胞毒性是潜在的ototoxins和確定了五個額外的抗癌治療的潜在ototoxins [ 39 ]。