Skeletal muscle accounts for 40% of the total body weight and is mainly composed of differentiated muscle fibers, which leave the cell cycle irreversibly. After adult muscle injury, resident stem (satellite) cells (SC) [1], which are usually at rest, re-enter the cell cycle and generate myocytes, which will participate in the reconstruction or repair of myofibrils. As we all know, skeletal muscle tissue has an intrinsic significant regenerative potential, but in the case of serious and long-term injury, this potential will be damaged. In particular, it has been reported that skeletal muscle tissue can compensate up to 20% of muscle mass loss, but beyond this threshold, the recovery of natural muscle tissue structure and function cannot be achieved [2]<br>
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