Arginine ketoglutarate [ 16856-18-1 ] (3 g 3 times in 1 day) given orally to patients with liver cirrhosis on a high protein
diet decreased plasma ammonia and free serum phenols. The decrease in ammonia was owing to increased urea
synthesis, whereas the decrease in serum phenols was owing to their improved oxidative decompn. No stimulation of
insulin secretion was obsd.