Flgs. 1 to 7. Penaeus monodon ~vl thw hlte spot syndrome. F i g A Photograph of carapace removed from P monodon showing white spots ranging from barely visible to 3 mm in diameter. Scale bar = 1 cm.Fig.2. Llght micrograph of cuticular epidermis under the cephalothorax exoskeleton (C) showlng basophilic ~nclusions in hypertrophied nuclei of degenerated cells (arrows). Scale bar =10 pm. Fig. 3. Transmission electron micrograph of ultrathin section of infected tlssue from beneath the cephalothoracic exoskeletal cuticle (C) showing viral particles in the necrotic area and in a hypertrophied nucleus (arrow). Scale bar = 0.5 pm. Fig& Transmission electron micrograph of negatively stained purified vir~onss how~nga tall-like projection (P)e xtending from one end of the virus.Scale bar = 0.1 pm. Fig.Transmission electron micrograph of negatively stained non-enveloped nucleocapsid sho~vlngth e crossstriations on the capsld formed by the ring subunits (arrows). The rings are allgned perpendicular to the longitudinal axls of thecapsid. Scale bar = 0.1 pm. -Fig-. 6 . Ethid~umb romide-sta~neda garose gel of PniNOBIII DNA extracted from purified vlrions. A single molecule of DNA is observed In the gel. Lane l: h phage DNA Hind 111 fragment marker. Lanes 2 to 4: extracted PmNOBIII DNA from each of 3 respective preparations. Fiql 7. Ethidium bromide-stained agarose gel of PmNOBIII DNA digested with Hind I11 restriction endonuclease. At least 22 DNA fragments (arrows) can be identified in this gel. Lane 1: h phaye DNA Hind I11 fragment marker. Lane 2: PmNOB 111 DNA Hind 111 restriction endonuclease fragments. Lane 3: 1 kb DNA ladder