Therefore, the surface charge of the particles<br>showed the positive charge of tartaric. Entrapment efficiency of<br>the obtained NLCs was varied between 59.4 and 85.7%. <br><br>The<br>satisfying results of entrapment efficiency attributed to the<br>particular inner structure of NLC, where the use of liquid lipid<br>gives rise to a less compact structure compare with SLN, able to<br>accommodate larger amounts of drug<br><br>And the<br>entrapment efficiency was the highest, arriving up to 85.7%, when<br>NLC prepared with VP–b-CD–TA by co-evaporated method. <br><br>In<br>conclusion, the VP–b-CD–TA COE-loaded NLC system, which had<br>good ability to encapsulate drug and displayed favorable<br>physicochemical characteristics, was selected for further morphology and crystal form study
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