With the rapid developments in the

With the rapid developments in the life sciences and the emer-
gence of a large number of substances for analysis, bioanalytical
techniques have faced unprecedented challenges and high-
throughput screening techniques are called for urgently. 1–4
Compared with conventional assay technologies, such as planar
arrays, 5–7 bead-based suspension assays provide more molecular
binding sites and effectively improve the sensitivity, and thus
have become more and more intriguing. 8–12
A key technology of bead-based assays is how to obtain a large
number of encoded and distinguishable microbeads. Fluores-
cence barcoding technology based on organic fluorophore-
encoded microbeads has attracted considerable attention for
multiplexed gene and protein screening. 9,13–18 However, poly-
meric beads optically encoded with organic fluorophores have
many limitations, such as photobleaching and the narrow exci-
tation spectra of dyes. QDs, a type of newly developed inorganic
nanocrystal, have become a promising fluorescent material used
to encode the beads, which has further promoted the develop-
ment of fluorescence encoded bead-based multiplexed analysis
technology. 17,19 Taking conventional organic dyes for

結果 (中文) 1:

随着生命科学与埃米尔-快速发展大量的物质进行分析，生物分析 gence技术面临着前所未有的挑战和高吞吐量筛选技术是迫切要求。1-4相比常规测定技术，如平面数组，5 – 7 珠悬浮检测提供更多分子结合位点和有效地提高灵敏度，从而已经变得越来越有趣。8-12基于珠的检测的关键技术是如何获取大区分和编码微球的数目。荧光灯-基于有机荧光-荧光条形码技术编码的微球已引起相当瞩目多路复用的基因和蛋白筛查。9，13-18 然而，多晶硅梅里克珠光学编码与有机荧光团有很多的局限性，如光漂白和窄锥细胞的兴奋-张力的染料光谱。量子点，一种新开发的无机纳米晶材料，已成为有前途的荧光材料，使用要编码的珠子，进一步促进了发展-对荧光编码珠基于多路复用的分析技术。17,19 以常规有机染料

結果 (中文) 3:

随着生命科学的迅速发展和新兴—大量物质的分析技术，分析技术面临着前所未有的挑战和高—迫切要求吞吐量筛选技术。1 4与传统的检测技术，如平面阵列，5，7珠为基础的悬浮液检测提供更多的分子结合位点，有效提高灵敏度，从而变得越来越有趣。8 12珠为基础的检测的一个关键技术是如何获得一个大编码和识别微球数量。荧光—基于有机荧光团的荧光条形码技术—编码微球已经引起相当大的关注，复用基因与蛋白筛选。9.13–18然而，聚—该珠光学编码与有机荧光染料有很多局限性，如漂白和狭窄的激发—染料进行光谱。量子点，一种新开发的无机物纳米晶，已经成为一种很有前途的荧光材料的应用要编码的珠子，这已经进一步促进了发展—基于荧光编码的微珠复用分析技术。以传统的有机染料17,19