摘要：成骨细胞是骨形成与生长的重要细胞，负责骨基质的合成、分泌和矿化。

摘要：成骨细胞是骨形成与生长的重要细胞，负责骨基质的合成、分泌和矿化。机械力的刺激作用对成骨细胞生长、发育、修复和凋亡发挥着重要作用。体内的力学环境比较复杂，用体外给予单种力学加载的方法可有效的消除其他因素的干扰，可以通过控制加载力的方式、大小、频率、时间等来研究机械力刺激对成骨细胞增殖和分化的影响。体外加载力的方式大概包括流体剪切力、离心力、压力、机械张力和机械振动等。本文通过近年来国内外有关机械力对体外培养成骨细胞增殖和分化的影响的研究进行综述。
关键词：机械力，成骨细胞，生物学活性，流体剪切力，离心力，压力，机械张力，机械振动

結果 (英文) 1:

Abstract: the osteoblasts are bone formation and growth of cells, is responsible for the synthesis and secretion of bone matrix mineralization. Effects of mechanical stimulation on osteoblastic growth, development, repair, and apoptosis plays an important role. Body mechanical environment is complex, with vitro single mechanical load methods can be used to eliminate other factors interfere, you can control how the load, size, frequency and time to study the mechanical stimulation on Osteoblast proliferation and differentiation of. Loaded force probably consisted of fluid shear, centrifugal force, pressure, mechanical vibration and mechanical tension. Through mechanical forces at home and abroad in recent years on cultured Osteoblast proliferation and differentiation of research were reviewed.Key words: mechanical and osteogenic cells, biological activity, and fluid shear, centrifugal force, pressure, mechanical tension, machine vibration

結果 (英文) 3:

Abstract: osteoblasts are important cells in bone formation and growth, which are responsible for the synthesis, secretion and mineralization of bone matrix. The stimulating effects of mechanical forces play an important role in the growth, development, repair and apoptosis of osteoblasts. The in vivo mechanical environment is more complex, in vitro given single mechanical loading method can effectively eliminate other factors of interference, can by controlling the force loading pattern, size, frequency, time and to study the mechanical stimulation on osteoblast proliferation and differentiation. The way of in vitro loading may include fluid shear stress, centrifugal force, pressure, mechanical tension, mechanical vibration, etc..In this paper, the effects of mechanical forces on the proliferation and differentiation of osteoblasts in vitro were reviewed in recent years. Key words: mechanical force, osteoblast, biological activity, fluid shear force, centrifugal force, pressure, mechanical tension, mechanical vibration