A previous double-blinded, placebo-controlled, par- allel trial found that daily consumption of YIT10347 helps to improve upper GI symptoms in patients with H. pylori-associated gastritis (Miki et al., 2007). Ad- ditionally, an open-label trial found beneficial effects on serious FGID (Urita et al., 2015) and a double-blind, placebo-controlled, crossover trial found positive ef- fects in healthy adults (Gomi et al., 2015).