Analysis of the results confirmed that rehabilitationof patients using both PNF and manual therapy hada statistically significant impact on reducing pain andimproving the performance of daily activities of femaleswith cervical spine pain. However, both in theshort (after two weeks) and the long term (after threemonths) PNF method proved to be more effective.When treating patients with degenerative changes painfree therapy based on indirect treatment and active participationof the client is recommended. Principles ofmotor learning, treatment on levels of body structuresand activity should be considered. It is useful to workwith PNF patterns which mimic functional ADLs.