The process industries have production, storage and use of flammable chemicals material units. Therefore, these industrials are most apt and prepared industries for facing the risks and explosions [1]. Always fire and explo- sions have enormous implications for human resources and financial capital. For example, in 1997, the explo- sion of pressure pipeline in the French Vitzan Petrohemica occurred because of leakage of liquid gas and killed 57 members of the industry staff [2]. Also, in 1992, release of light Nephatan from the pressurized tank resulted in the explosion in the Bambi refinery and 35 experts were killed [3]. According to risk matrixes, the risks with consequence of death are the unacceptable and critical risks [4] [5]. The lack of safety inspections has basic role in such accidents. So, the planning of safety inspection programs, risk assessment detonation and fire and deter- mine preventive measures based safety is essential in the different units of the refinery. The items of inspection programs and risk assessment detonation and fire must be including identifying the warehouses of flammable materials, value and operating parameters of material, leakage paths of material, identifying places and storage locations for flammable materials, value and their operating parameters, possible leakage paths, identifying sce- narios possible and consequences of accident, identifying of preventive measures fire and explosion [6]. Al- though the processing facilities and equipment are used for productivity, profitability and also wealth production, but they have important (main) potential for damaging human being, property and the environment. Since the number of refineries and their products increased thus exposure to hazards is also higher for workers. For exam- ple, the accident of Felix borough in England in 1984 left 28 dead and 26 injured [7]. Another case of chemical accidents occurred in December 1984 in Bhopal, India [8]. Also, because of leakage and firing of oil (petro- leum), from gas platform of BP company in Mexico gulf, 11 people died and the damage amounted to more than 40 billion $ and caused 22 percent decrease in shares and 63 percent decrease in profits [9]. In order to prevent the accidents, assessment and identification of the accidents and risks in the refinery units are very important. For multiple injuries resulting from accidents in processing industries are illness cases and cause injury and death, damages to property, environmental pollutions, decreasing production and profits, loss of reputation and credibility in the organization. In the following, the common scenarios relating to fire has been investigated in oil and gas industries.