NOTE: Patient sample red cell indic

NOTE: Patient sample red cell indices (Wintrobe indices or MCV, MCH, MCHC) should be
monitored routinely to detect random errors, instrument malfunction, or spurious results.
If semiautomated methods are used, indices should be calculated. On many automated
instruments, the MCHC is the most useful parameter to ensure accuracy of the red cell
parameters in individual patient samples. Since MCHC varies over a narrow range, an abnormal
MCHC will often flag potentially spurious red cell parameters. Truly elevated MCHCs may be
seen with spherocytosis, while decreased MCHCs can accompany a low MCV in severe iron
deficiency anemia. If such RBC abnormalities are not present on the blood film, one or more
of the measured RBC parameters is likely erroneous. Incorrect data may be due to instrument
malfunction or to problems with the blood sample itself. Some examples include: spuriously
elevated MCVs and MCHCs with cold agglutinins, falsely elevated MCHCs with lipemia and
plasma paraproteins, spuriously low MCHCs with leukocytosis and osmotic effects such as
hyperglycemia altering MCV. MCV and MCH are fairly constant for each patient, and monitoring
these indices in a delta check error detection program may provide rapid patient-based detection
of instrument malfunction or specimen misidentification.
Evidence of Compliance:
✓ Written procedure defining the criteria used to monitor the red cell indices to detect random
errors AND
✓ Record of action taken when RBC indices are in question, including the reporting of results

結果 (中文) 1:

NOTE: Patient sample red cell indices (Wintrobe indices or MCV, MCH, MCHC) should bemonitored routinely to detect random errors, instrument malfunction, or spurious results.If semiautomated methods are used, indices should be calculated. On many automatedinstruments, the MCHC is the most useful parameter to ensure accuracy of the red cellparameters in individual patient samples. Since MCHC varies over a narrow range, an abnormalMCHC will often flag potentially spurious red cell parameters. Truly elevated MCHCs may beseen with spherocytosis, while decreased MCHCs can accompany a low MCV in severe irondeficiency anemia. If such RBC abnormalities are not present on the blood film, one or moreof the measured RBC parameters is likely erroneous. Incorrect data may be due to instrumentmalfunction or to problems with the blood sample itself. Some examples include: spuriouslyelevated MCVs and MCHCs with cold agglutinins, falsely elevated MCHCs with lipemia andplasma paraproteins, spuriously low MCHCs with leukocytosis and osmotic effects such ashyperglycemia altering MCV. MCV and MCH are fairly constant for each patient, and monitoringthese indices in a delta check error detection program may provide rapid patient-based detectionof instrument malfunction or specimen misidentification.Evidence of Compliance:✓ Written procedure defining the criteria used to monitor the red cell indices to detect random错误和✓ 记录时红细胞指数有问题，包括报告的结果而采取的行动

結果 (中文) 3:

注：病人样本红细胞指数（温氏法指数或MCV，MCH，MCHC）应
例行监督检测的随机误差，仪器故障，或虚假的结果。
如果使用半自动方法，指标应计算。在许多自动化仪器的
，MCHC是保证病人样品中的红细胞
参数精度的最有用的参数。由于平均变化在很窄的范围内，一个异常
MCHC会标志可能寄生红细胞参数。真正的升高可能
母婴健康院见球形红细胞增多症，降低母婴健康院可以陪在严重的铁缺乏性贫血MCV
低。如果不存在这样的红细胞异常的血液膜，一个或多个的测量红细胞参数是可能的错误。错误的数据可能是由于仪器的故障或与血液样本本身的问题。一些例子包括：虚假地
高架MCV和母婴健康院与冷凝集素，假性升高与血脂及血浆
母婴健康院副蛋白，非常低的增多和渗透影响母婴健康院等高血糖改变
MCV。MCV和MCH为每一个病人都相当稳定，这些指标和监测
三角检查错误检测程序，可以提供快速的基于患者的检测
仪器故障或标本误认。
符合性证据：
✓书面程序定义用于监测红细胞指数检测误差和随机

取当RBC指数是问题行为✓记录标准，包括结果的报告