Among techniques used to classify lipoprotein subclasses in greater detail, NMR quantifies particles according to density and particle size, and NMR-LSP characteristics were shown to predict vascular complications in observational and clinical studies (36, 37). However, clinical data on the effects of berries or purified anthocyanins on NMR-LSP are scarce. In reference to the noteworthy study by Zunino et al., FDS (∼320 g of frozen strawberries) were shown to decrease the concentrations of NMR-derived small HDL cholesterol particles and increase LDL particle size, whereas no effects were noted on VLDL- and LDL-related particle concentrations in obese adults (14). Compared with these findings, our 12-wk intervention shows the effects of a higher dose of FDS to decrease only the small LDL particle concentrations, when compared with the control group. Small LDL particles were significantly correlated with increased atherogenicity (38), and thus our findings may have implications in the primary prevention of atherosclerosis in obese adults with above-optimal total and LDL cholesterol concentrations.