Plastic debris in the oceans is a major and growing problem in global environmental pollution.Results showed that fertilization of the embryos was not affected by plastic leachates, but the developments of D-veliger larvae, including survival, deformity, and shell height, were significantly affected by plastic leachates from both PB1 and PB2 compared to the controls of filtered seawater.We speculate that compounds leaching from plastic bags are responsible for the observed toxicity.Therefore, leaching toxicity from plastic debris should be considered when assessing the risks of plastic pollution in the oceans.