At present, cancer remains one of the major causes of human death in the world.
Traditional cancer treatments, including surgery, chemotherapy, and radiotherapy,
usually fail to radical cure because of the recurrence and metastasis of cancer.
Chemotherapy, one of the most commonly used cancer treatments, has contributed
greatly to reductions in cancer mortality. However, chemotherapeutic agents often
cause adverse effects such as liver and kidney damage, hair loss, nausea, and cardiac
toxicity [ 1 – 3 ]. These systemic hazards are generally due to the lack of drug specifi city
toward tumorigenic cells [ 4 ]. What’s more, chemotherapy usually leads to drug
resistance and causes treatment failure [ 5 ]. Therefore, there is an urgent need for the
development of novel anticancer strategy.
At present, cancer remains one of the major causes of human death in the world.Traditional cancer treatments, including surgery, chemotherapy, and radiotherapy,usually fail to radical cure because of the recurrence and metastasis of cancer.Chemotherapy, one of the most commonly used cancer treatments, has contributedgreatly to reductions in cancer mortality. However, chemotherapeutic agents oftencause adverse effects such as liver and kidney damage, hair loss, nausea, and cardiactoxicity [ 1 – 3 ]. These systemic hazards are generally due to the lack of drug specifi citytoward tumorigenic cells [ 4 ]. What’s more, chemotherapy usually leads to drugresistance and causes treatment failure [ 5 ]. Therefore, there is an urgent need for thedevelopment of novel anticancer strategy.
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