In the resistance induction procedu

In the resistance induction procedure, there was a constant reduction in the sensitivity zone over each doubling of enrofloxacin concentration. The colonies found to be resistant at each concentration were sequenced. A comparison of the sequences of the colonies obtained at each step revealed that with respect to the initial E.coli ATCC25922 strain, resistance induction had resulted in a gyrB mutation at the Lys447 residue, which had been substituted for arginine

結果 (中文) 1:

抗性的诱导过程中，有一个恒定的降低的灵敏度区的恩诺沙星浓度每增加一倍。发现是有抵抗性的各浓度的菌落进行测序。在每一步获得的菌落的序列的比较表明，相对于初始的大肠杆菌ATCC25922菌株，gyrB基因突变导致抗性的诱导在lys447残余物，已被精氨酸取代的

結果 (中文) 2:

在电阻感应程序，人们对恩诺沙星的浓度每增加一倍的敏感区不断减少。殖民地被发现在每个浓度测定抗。在每个步骤中获得的殖民地的序列比较发现，相对于初始的大肠杆菌，诱导抗病性导致了在lys447残留的gyrB基因突变，已取代精氨酸

結果 (中文) 3:

在电阻感应过程中，有的敏感性区域不断减少恩诺沙星浓度每增加一倍。殖民地发现能够抵御每个浓度被测序。殖民地获得了在每个步骤的序列的比较显示，在初始的大肠杆菌 ATCC25922 应变，在 Lys447 残留，已取代精氨酸 gyrB 基因突变导致电阻感应