Kidney is mainly composed of kidney units, each of which has 1000000 or so of the kidney. The renal unit includes renal body and its corresponding renal tubules, renal body in the renal cortex, renal tubules in the renal medulla. Ju county people's Hospital Department of Nephrology; Cui Zhaoshan
renal corpuscle by glomerular and renal capsule glomerulus is by the ball separation of arterioles of 5 ~ 8 branch composed of a group of capillary network. A small amount of the capillary was filled with a small amount of the system, and the system was composed of the mesangial matrix and a small number of mesangial cells. The glomerular capillary wall is divided into 3 layers: the inner layer is endothelial cells, basement membrane, the middle layer is epithelial cells,These 3 layers are called "glomerular filtration membrane", which is the important physiological function of kidney. The special structure of the small artery and the small artery of the small artery in the glomerular is a special structure, which is composed of the cells and the dense patches. In the cytoplasm of the cells of the cell, the secretory granules are contained in the cytoplasm. The immune fluorescence shows that these particles contain renin, and more than 90% of the human body is secreted by the cells. When the renal ischemia, renal artery pressure drop can stimulate renin secretion, so the ball next to the cell and said the pressure of the cells". The dense patches are evolved from the distal tubular epithelial cells,The contents of the cell are small particles, which can change the capacity and the concentration of sodium ions in the distal tubule. Therefore, it is called "sodium sensitive cell", which can regulate the secretion of renin in the cell.
kidney tubules can be divided into proximal tubule (including nearly tubule and Henle's loop down a rough section), thin segment of medullary loop, distal tubules (including loops of Henle thick ascending limb and the distal convoluted tubules). Proximal tubular reabsorption of fluid of kidney spherule filtration (urine) in almost all glucose, amino acid and protein, and 65% of the Na, 85% of the water and 50% urea, but also to the luminal secretion H ', ammonia, creatinine, hippuric acid.Is an important part of the heavy absorption of a large number of useful substances in the urine and secretion of certain waste. Mtal is diluted urine is the key, the epithelial cells to NaCl active reabsorption and not associated with water absorption, so that the section of the tubular fluid become hypotonic fluid, urine dilution become possible. The function of the distal tubule is to continue to absorb water and Na. }, and to secrete K, H and ammonia, to maintain the blood acid-base balance. Aldosterone can promote the epithelial cells of the segment to absorb Na, K, anti diuretic hormone can improve its water absorption, so that urine concentration, urine volume decreased.
The main physiological function of the kidney is to generate urine, and to drain the body's metabolic end products and some waste, poison, and at the same time by re absorption of the retention of useful substances, regulating water, electrolyte and acid-base balance. In addition, fair in the kidney secretion some important endocrine hormones (such as renin, erythropoietin (EPO), prostacyclin), and insulin, gastrin, parathyroid hormone and other hormone destroy living place
正在翻譯中..