In an effort to increase the overal

In an effort to increase the overall efficiency of this synthesis,
we explored alternate amidation methods. Of the methods tried,
the most valuable involved carboxylate activation using
carbonyl diimidazole (CDI), as shown below.
This approach was found to be very clean, but separation of
the product from the solvent and by-products proved problem￾atic. Ultimately however, it was found that the CMPO silane
reaction mixture could be used in the monolayer deposition
directly, with no ill side-effects on monolayer quality.
One method for enhancing selectivity for the larger actinide
cations over the more common transition metal cations is to
enlarge the chelating cavity of the ligand. Thus we also wanted
to prepare the corresponding homolog (structure 4). This was
accomplished via conjugate addition diethylphosphite to tri￾fluoroethyl acrylate, as shown below. Once again, the tri￾fluoroethyl ester was purified by vacuum distillation in good
yield.9 Mixing 4 with neat 2 resulted in a modest exotherm, and
was found to be complete in approximately 100 minutes. Once
again, attempted distillation resulted in partial decomposition of
the product, so the trifluoroethanol was removed under vacuum
and the desired CMPO silane (5) used directly

結果 (中文) 1:

在努力提高整体效率的这种合成，我们探讨了备用的酰胺化方法。方法试过了，最有价值的涉及甲酸激活使用咪唑羰基 (CDI)，如下所示。这种方法被发现非常干净，但分离的从溶剂和副产品产品证明问题阿蒂奇。最终，这可是发现 CMPO 硅烷反应混合物可用于单层沉积直接地与单层质量无不良副作用。为加强对较大的锕系元素的选择性的一种方法在更多常见的过渡金属阳离子的离子是放大的螯合配体的腔。因此我们也想要准备相应同源 （结构 4）。这是通过共轭加亚磷酸二乙酯三氟丙烯酸，如下所示。再次，良好的真空蒸馏法纯化三氟酯yield.9 混合与整洁 2 4 导致谦虚的放热，和被发现在大约 100 分钟完成。一次再次，企图的蒸馏导致部分分解的产品，所以乙醇被去除了在真空和所需的 CMPO 硅烷 (5) 直接使用

結果 (中文) 3:

在努力提高这种合成的整体效率，我们探讨了备用的酰胺化的方法。尝试的方法，最有价值的涉及羧酸盐激活使用羰基二咪唑（CDI），如下图所示。这种方法被认为是非常干净的，但分离从溶剂和副产品的产品证明￾化问题。不过最终，发现CMPO硅烷反应混合物可用于单层沉积直接，没有不良的副作用，单层质量。一种提高较大的锕系元素的选择性的方法在更常见的过渡金属阳离子的阳离子是扩大配位体的螯合腔。因此，我们也希望准备相应的同源物（结构4）。这是通过共轭加成到三氟乙基丙二亚膦酸酯￾完成，如下图所示。再次，三￾氟酯是由良好的真空蒸馏提纯产量。9混合4整洁2导致在一个适度的放热，和被发现是在约100分钟内完成。一旦再次，尝试蒸馏导致部分分解产品，所以三氟真空下被拆除和所需的CMPO硅烷（5）直接使用