Intracranial atherosclerotic diseas

I
ntracranial atherosclerotic disease is a major cause of isch-
emic stroke worldwide and the most common cause in the
however, a shift has taken place toward imaging the intracra-
nial vessel wall rather than the lumen as a result of advanc-
ing knowledge on the development of atherosclerotic plaques.
Nowadays, it is common knowledge that outward arterial
Asian population.
1
Patients suffering from intracranial athero-
In subjects with
sclerosis have a high subsequent stroke risk.
1
asymptomatic middle cerebral artery (MCA) stenosis, the
overall annual stroke risk is 2.8%, whereas in patients with
symptomatic middle artery stenosis the risk is even 4 times
remodeling occurs, enabling plaques to develop without lumi-
nal narrowing.4,5
From histopathologic studies, examining the carotid and
coronary arteries, it is known that plaques containing a large
high.2 For many years, lumenography-based methods were
used to assess intracranial atherosclerotic disease by means
of luminal narrowing, and it was thought that stenosis grade
necrotic core or intraplaque hemorrhage and of a soft compo-
sition are typically at risk for plaque rupture.6–8 Furthermore,
was an accurate reflection of disease burden.
3
In recent years,
several magnetic resonance imaging (MRI) studies have

結果 (中文) 1:

我ntracranial 动脉粥样硬化性疾病是焦袂康酸-主要原因世界范围内的主位中风和中最常见的原因然而，发生了变化对成像 intracra-nial 血管壁，而不是由于垫付的款项-腔ing 知识对动脉粥样硬化斑块的发展。如今，这是常识，向外动脉亚洲的人口。1患者患颅内动脉粥样-患者硬化有高随后中风的风险。1无症状性大脑中动脉 (MCA) 狭窄整体年度中风的风险是 2.8%，而在患者症状性动脉狭窄的风险是甚至是 4 倍重塑的发生，使斑块没有光民-发展宇空实验室 narrowing.4,5从组织病理学研究，检查颈动脉和冠状动脉，可知，含有大量的斑块high.2 很多年，基于 lumenography 的方法了用来评估颅内动脉粥样硬化疾病的手段管腔缩小，认为那狭窄的等级坏死的核心或可以出血和软的前奏曲 — —组成通常处于危险的斑块 rupture.6–8.此外，是疾病负担准确所。3近年来，几种磁共振成像 (MRI) 研究有

結果 (中文) 3:

我
颅内动脉粥样硬化是缺血性中风的主要原因—
主世界和中风的最常见原因
然而，转变了对成像的脑的地方—
NiAl血管壁而不是管腔由于先进—
了解动脉粥样硬化斑块的发展。
如今，它是外动脉的常识
亚洲人口。
一
例颅内动脉粥样硬化—
在受试者
硬化症有较高的中风风险。
一
无症状性大脑中动脉（MCA）狭窄的
整体年中风风险为2.8%，而在患者
有症状的中动脉狭窄的风险甚至是4倍
重塑的发生，使斑块发展无光—
最终缩小。5
从组织病理学的研究，检查颈动脉和
冠状动脉，它是已知的，含有一个大的斑块
高。2多年来，管腔造影为基础的方法
用于评估颅内动脉粥样硬化性疾病的方法
的管腔狭窄，并认为狭窄级
坏死核心或斑块内出血和软组—
位置通常在斑块破裂的风险。6–8此外，
是一个准确的重新fl检验疾病负担。
三
近年来，
几种磁共振成像（磁共振成像）的研究