For example, mobile operators who used to have a dominating role as intermediary for mobile telecom services, linking service application and technology providers with individual consumers and enterprise customers, will in IoT applications see their position threatened by other actors. For example, IoT based remote patient monitoring, implying increasing access to care and decreasing health care costs, require re-organization, sometimes radical, of relations between patients, care providers, health care support units, technology providers, hospitals, wireless system providers and others. Intermediation in the network will change, and actors, including objects, will take new roles as intermediaries.