The present study aimed to investigate whether an oral splint (Fig. (Fig.1A),1A), commonly used for dental treatments of temporomandibular joint disorders, clenching, and bruxism, might be therapeutically effective to ameliorate TS‐related tics. To this end, we examined tic scores in 22 TS patients (Supporting Information) using the Tic Symptom Self‐Report, which consists of motor and phonic tic scores (0–60; higher scores indicating severer states).3 Mean age at TS onset was 5.9 years, and mean age at the first hospital visit was 17.2 years. Mean motor and phonic tic scores before splint application were 15.3 and 15.1, respectively. Individual scores immediately decreased to 11.0 and 8.2 at the first hospital visit while wearing the splint; average reduction rates were 30% and 43%, respectively (Fig. (Fig.1B).1B). The accompanying videos clearly demonstrate the immediate effects on the motor tics of 2 patients: Both oral and ocular tics were improved. Sixteen (72.7%) of the 22 patients exhibited improvements in both motor and phonic tics: 10 of 14 children (