n HDFs, treatment with both type of exosomes had no effect on the level of fibronectin, although iMSC-exo were found to be more potent in inducing fibronectin secretion than MSC-exo. An increase in collagen level was observed after MSC-exo or iMSC-exo treatment in HDFs (p < 0.05), although no significant difference was found between two exosome types.