This study aimed to understand the relationship between dietary, serum, and macular carotenoids, and relational memory. Our results revealed that serum lutein was significantly related to two metrics of relational memory performance even after adjusting for significant covariates. While this study was correlational, it lays the groundwork for subsequent research in this area. Further intervention studies where carotenoids are assessed in the macula and serum must be conducted to better understand this relationship, particularly in participants withoverweight or obesity.