NMR-determined lipoprotein subclass profiles (LSPs) was performed in first-thaw plasma specimens using a 400-MHz proton NMR analyzer at LipoScience as described previously (22). Plasma ellagic acid was measured using HPLC-UV procedures as described previously by Seeram et al. (23). The minimum detectable concentration of ellagic acid in our assay was 3.5 ng/L. The interassay CV was 7.8%.