Through CVC bundle education, training, design, publicity and promotion, the cognition of CVC bundle in critical units was effectively improved by 90.6%. Using checklists as a two-way communication and reminder mechanism of medical care, the retention rate of CVC in patients decreased from 18.1% in January to March 2019 to 14.1% in October 2019. With the help of action, CVC improved the convenience of drug exchange, the CVC bundle was implemented in critical units, and the integrated rate of central venous catheter was 93.7%.<br>
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