Remember that not all nucleophiles

Remember that not all nucleophiles will successfully undergo Michael additions-you must bear
this in mind when making a 1,3-disconnection of this type. Most reliable are those based on nitro-
gen, sulfur, and oxygen (Chapter 1D).
Qur second example is an amine structurally similar to the `deadly nightshade' drug, atropine,
which has the ability to calm involuntary muscle movements.'fhere is a 1,3一relationship between the
amine and ketone functional groups, and 1,3-disconnection takes us back to piperidine and an
nncatnratP日卜PYnne

結果 (中文) 1:

记住不是所有的亲核试剂将成功接受迈克尔加成反应-你必须记住制作这种类型 1，3-网络断线时铭记这一点。最可靠的是那些基于硝基-根、 硫和氧 (第 1 章)。古兰经第二个例子是胺结构类似于 '颠茄' 药物，阿托品，其中有能力冷静不随意肌运动。 ' fhere 是 1，3一relationship 之间胺类和酮官能团和 1，3-网络断线将我们带回到哌啶和nncatnratP日卜PYnne

結果 (中文) 3:

记住，不是所有的亲核试剂将成功地接受米迦勒加入你必须承担这一点使1,3-disconnection这种类型时。最可靠的是那些基于硝基—根，硫和氧（第1章）。我们的例子是胺的`龙葵的药物结构相似，阿托品，具有冷静的不自觉的肌肉运动的能力。"fhere是1,3一关系胺和酮官能团，并1,3-disconnection带我们回到哌啶和nncatnratp日卜pynne