398. Pneumonol Alergol Pol. 1994;62(1-2):46-50.
[Elastic recoil pressure in radiation induced injury of the lung].
[Article in Polish]
Pierzchała W(1), Zurek M.
Author information:
(1)II Katedry i Kliniki Chorób Wewnetrznch Sl.AM w Katowicach.
The study was carried out on 34 females, age range 31-62 years, mean 46 years. It
was conducted in the early phase, 3 months after introduction of the radiotherapy
with X-rays. The results were compared with the initial values measured
immediately after surgical removal of the tumour. The irradiation dose was 40 Gy
to the sternum area and 35 Gy to the middle part of the axilla. Volume and
capacity indices, bronchial resistance, small airway function parameters and
mechanical properties of the lungs were studied. In the group of younger females
(age < 46 years) a significant increase of the retraction index was noted (RC =
P.TLC: TLC) following radiotherapy and a coexistent decrease of thoracic gas
volume (TGV). In the whole group 13 patients reacted to radiotherapy with a left
shift of the V/Pel curve, demonstrating an increase of elastic recoil. This group
of patients also showed a marked decrease of TGV. These observations demonstrate
that in a part of the patients treated with X radiotherapy a new equilibrium
instated between elastic recoil pressure and lung capacity.
PMID: 8075611 [PubMed - indexed for MEDLINE]