The magnitude of the marked change in polyunsaturatesand the opposite trend in these changes occurring in plasmaFFA and adipose tissue on the one hand, compared withbrain and liver TG on the other, imply net fatty acid fluxfrom adipose tissue via blood to liver TG and other tissues,including brain. The difference in fatty acid content andprofile between the control and ketogenic diets was notresponsible for the marked change in tissue distribution ofarachidonic acid and docosahexaenoic acid because thesefatty acids were not present in either diet. The brain was