The ADC image is a display of ADC values for each voxel in an image. Most CS PCa have restricted/impeded diffusion compared to normal tissues and thus appear focal markedly hypointense on ADC maps. Because mp-MRI data of PCa, in particular CS PCa, are often scarce and costly to obtain, training an accurate classifier leveraging recent advances in data-hungry deep learning, e.g., convolutional neural networks (CNNs), for PCa detection and aggressive assessment based on mp-MRI images is significantly challenging.