Notably, there were a number of exclu sions in this study, including hospitaliza tion, diabetes, renal insufficiency (even mild), immunodeficiency broadly defined, and cellulitis associated with peripheral vascular diseases. Although purulence of the cellulitis was not an exclusion, 87% did not have it at all and, of those who did, a volume >1 mL by report or observation was cause for exclusion. Further clinical trials are needed to determine whether these results are generalizable to other out patient populations. Confirmatory data from other studies also will be critical for increasing physicians' confidence that they know cellulitis when they see it and that MRSA coverage is unnecessary in uncom plicated cases in outpatients