Management issues addressed include the responsibility of the quality of the whole measurement process, which needs to include the sampling procedure. Guidance is given on the selection of the most appropriate approach for any application, and whether one initial validation of the system is sufficient, or whether there is a need for ongoing monitoring of the uncertainty from sampling using quality control of sampling. The extra cost of estimating uncertainty is also considered in relation to the cost savings that can be made by knowing the uncertainty of measurement more reliably.