In this study, we evaluated total intracranial plaque burden
and plaque morphology and compared morphological features
of symptomatic lesions to those of asymptomatic lesions in
patients with a symptomatic MCA stenosis. We demonstrate
that (1) most lesions were found in the distal ICA, intracranial
bifurcation of the ICA, and in the M1 segment of the MCA,
(2) besides the confirmed culprit MCA lesion, most patients
had additional asymptomatic lesions, and (3) eccentric lesions
were associated with focal thickening and asymptomatic
lesions, whereas symptomatic lesions did not have any spe-
cific morphological features.