DiscussionThis is the first study s

DiscussionThis is the first study showing a preventive effect of GBR fermented by L. acidophilus on colorectal carcinogenesis in rats. In this study, we used ACF as a morphological marker and both SIM-ACF and MDF as dysplastic markers during colorectal carcinogenesis, as mentioned by a previous study [26]. We also measured the serum levels of pro-inflammatory cytokines and the colonic expressions of apoptosis-related proteins to investigate the associated anti-cancer mechanism. The results showed that FGBR inhibited preneoplastic lesions (ACF and SIM-ACF), reduced pro-inflammatory cytokines (TNF-α, IL-6 and IL-1β) and regulated apoptosis-related proteins (Bax, Bcl-2 and caspase-3). These findings suggest the potential of this novel fermented rice product for CRC chemoprevention.

結果 (繁體中文) 1:

討論
這是表示GBR的對大鼠結直腸癌發生由嗜酸乳桿菌發酵的預防作用的首次研究。在這項研究中，我們使用ACF作為形態標記和兩個SIM-ACF和中密度纖維板作為大腸癌發生過程發育異常的標記，如由先前的研究[26]中提及。我們還測量促炎性細胞因子和細胞凋亡相關蛋白的表達結腸的血清水平來調查相關的抗癌機制。結果表明，FGBR抑制癌前病變（ACF和SIM-ACF），降低促炎性細胞因子（TNF-α，IL-6和IL-1β）和調節細胞凋亡相關蛋白（Bax和Bcl-2和胱天蛋白酶-3 ）。這些結果表明這種新型大米發酵產品的化學預防CRC的潛力。

結果 (繁體中文) 2:

Flirt 是雙關語樣式

結果 (繁體中文) 3:

討論
這是首次發現嗜酸乳桿菌發酵的GBR對大鼠結直腸癌的預防作用。在這項研究中，我們使用ACF作為形態學標記，SIM-ACF和MDF作為結直腸癌發生過程中的异常增生標記，正如先前的研究所提到的[26]。我們還測定了血清促炎細胞因數水准和結腸凋亡相關蛋白的表達，以探討相關的抗癌機制。結果表明，FGBR可抑制癌前病變（ACF和SIM-ACF），降低促炎細胞因數（TNF-α、IL-6和IL-1β）和調節凋亡相關蛋白（Bax、Bcl-2和caspase-3）。這些發現表明這種新型發酵米製品對大腸癌具有潜在的化學預防作用。