In unravelling the mechanism of the

In unravelling the mechanism of the reaction, chemists protected the nitrogen atom with Iloc
(Chapter 25) before the reaction y,}ith benzaldehyde and found that a new product was formed that was clearly an E-alkene as its NMR spectrum contained SH 6.73 (1H, d, ] 16). This is too large a coupling constant even for axiallaxial protons and can be only trr}ns coupling across a double bond.
They quickly deduced that a simple aldol reaction had happened.
When the Boc protecting group was removed, the cyclization reaction occurred under very mild conditions but now a single diastercoisamer of the product was formed.
This isomer had one proton that could be clearly seen at $H 4.27 p.p.m.-well away from all the
rest. This is the proton marked in black between nitrogen and the phenyl group. It was a double dou-
blet with]=6 and 4 flz. Neither of these is large enough to be an axiallaxial coupling but h Hz is
within the range for axiallequatorial and 4 Hz for equatoriallequatorial coupling. The compom记
must have the conformation shown in the margin.
Treatment of this product with stronger base (NaOH) isomerized it to a compound in which

結果 (中文) 1:

在解体的反应机理，化学家保护劳工的氮原子(Chapter 25) 前反应 y，} ith 苯甲醛和发现，一种新产品，形成了明确电子烯烃及其核磁共振谱载 SH 6.73 (1 H，d，] 16)。这是太大，甚至为 axiallaxial 质子耦合常数，并且可以只 trr} ns 耦合跨一个双键。他们迅速推断简单羟醛缩合反应发生。当叔丁氧羰基保护组被删除时，环化反应发生在非常温和的条件下，但现在产品单一 diastercoisamer 成立。这同分异构体有一个质子，可以清楚地看到在 $H 4.27 p.p.m-远离所有休息。这是质子中用氮和苯基组之间的黑色标记。它是双斗与滚轴] = 6 和 4 flz。这些都不是足够大，可以 axiallaxial 耦合但 h Hz 是在 equatoriallequatorial 耦合 axiallequatorial 和 4 Hz 范围之内。Compom记必须有构象显示在页边空白处。该产品具有更强的基地 （氢氧化钠） 处理异构它到一个院子里，

結果 (中文) 3:

在解决了反应机理、化学保护的氮原子与Iloc（25章）在反应Y，}以苯甲醛和发现新产品形成明显的核磁共振谱中E-烯烃SH 6.73（1H，D，] 16）。这是太大，甚至axiallaxial质子耦合常数只能TRR } NS耦合在一个双键。他们很快就得出一个简单的羟醛缩合反应的发生。当Boc保护基团除去，环化反应发生在非常温和的条件下，但现在一个diastercoisamer产品的形成。这种异构体有一个质子，可以在4.27小时内美元-远离所有的清晰可见休息。这是在氮和苯基组之间的黑色标记的质子。这是一个双斗—] = 6和4均带。这些都不足以成为一个axiallaxial耦合但H赫兹的范围内为equatoriallequatorial耦合axiallequatorial和4赫兹。的compom记必须有在边缘显示的构象。具有较强的基本品治疗（NaOH）它在其中一个化合物的异构化