Inappropriate prescribing is highly prevalent and commonly associated with polypharmacy in older populations.11 17 However, rigorous evaluations of interventions seeking to address this are lacking. The findings of this review indicate that pharmaceutical care-based interventions appear to improve appropriate polypharmacy in older people based on observed reductions in inappropriate prescribing, especially when the provision of care involves a multidisciplinary element.25 27–33 CDS showed potential as an intervention, although this was evaluated in only one study.34