According to the statistics of the Ministry of health services, from 2010 to 2017, the most common infection site was blood flow infection in the intensive care unit of the medical center, in which the blood flow infection rate of the central venous catheter (CVC) was as high as 44%. Although CVC indwelling provides convenience for clinical treatment, the use of invasive catheters increases the risk of infection. Once bacteremia is caused, the mortality of patients will be increased (Sheng, Chen, 2017).<br>In order to improve the improvement value of the unit by 80%, the complete rate of combined care of central venous catheter in severe unit was from 56.9% to 91.4%.<br>Arrange CVC bundle care education and training, design promotional supplies to promote CVC bundle care, promote CVC bundle content and develop audit mechanism, design and evaluate CVC retention checklist, and plan CVC care related materials.<br>Through CVC bundle education, training, design, publicity and promotion, the cognition of CVC bundle in critical units was effectively improved by 90.6%. Using checklists as a two-way communication and reminder mechanism of medical care, the retention rate of CVC in patients decreased from 18.1% in January to March 2019 to 14.1% in October 2019. With the help of action, CVC improved the convenience of drug exchange, the CVC bundle was implemented in critical units, and the integrated rate of central venous catheter was 93.7%.<br>
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