摘要：目的 通过1:2病例对照研究，获得仙游县居民胃癌发生的饮食有害因

摘要：目的 通过1:2病例对照研究，获得仙游县居民胃癌发生的饮食有害因素及其相互间的交互作用，为胃癌在饮食方面的防治提供科学参考依据。
方法 收集2013年3月2015年7月在仙游县医院住院并经病理确诊的胃癌病例433例，并按胃癌调整死亡率高、中、低分层随机抽取8个村的健康居民按1:2进行个体匹配。通过问卷调查获取研究对象的一般情况、职业史、饮食习惯、饮食内容、消化道疾病史、家族肿瘤史、心理因素等。采用2检验对研究对象的婚姻状况、文化程度、职业等一般人口学资料的分布差异进行比较；用Cox回归分析计算相对危险估计值（odd ratio，OR值）、P值和OR值的95%可信区间；采用多因素Cox回归分析筛选胃癌发生主要危险因素；根据Bruzzi推荐的公式计算人群归因危险度。
结果 仙游县胃癌的可能危险因素主要有：饮食速度快、喜食干硬食物、高盐饮食、饭后劳作、吃腌菜；可能的保护因素主要有：牛羊肉、海带紫菜、洋葱、蔬菜、食用菌。
结论 仙游县胃癌高发与多种饮食因素有关，应采取一些积极的措施改善仙游县人群的饮食习惯，以减少胃癌的发生率。
关键词：胃癌 饮食 病例对照研究

結果 (英文) 1:

Objective: by 1:2 a case-control study, residents of Xianyou obtained gastric cancer diets harmful factors and their interactions with each other, for the prevention of gastric cancer diet provides scientific references.Collected March 2013 July 2015 in Xianyou County Hospital and 433 cases of pathologically confirmed stomach cancer cases, and adjusted for gastric cancer mortality is high, medium and low layered 8 randomly selected healthy residents in the village of 1:2 for individual matches. Through the questionnaire to obtain the object of study in General, occupational history, diet, dietary, gastrointestinal diseases, family history of cancer, and psychological factors. 2 test was used for the study of the marital status, education level, occupation, general demographic data, such as distribution differences compared using Cox regression analysis to calculate relative risk estimates (odd ratio,OR), 95% confidence interval p value and OR value using multivariate Cox regression analysis of major risk factors of gastric carcinoma under Bruzzi recommend formula to calculate population attributable risk.Xianyou County results may be risk factors for gastric cancer are: fast diet, eating dry food, high salt diet, working after dinner, eating pickles; possible protective factors are: kelp seaweed, onion, beef and mutton, vegetables and edible fungus. Conclusions the high incidence of gastric cancer associated with various dietary factors in Xianyou County, Xianyou County should take some positive steps to improve the eating habits of people in order to reduce the incidence of stomach cancer. Key words: diet for gastric cancer case-control studies

結果 (英文) 3:

Abstract: objective by 1:2 matched case control study, obtain Xianyou County of gastric cancer in residents of diet is harmful factors and their mutual interaction, to provide scientific basis for prevention and treatment of gastric cancer in the diet.
method to collect 2013 March July 2015 in Xianyou County hospital hospitalization and 433 cases by pathological diagnosis of gastric cancer, and according to the stomach cancer mortality is high, medium and low with stratified random sampling from 8 villages in the health of residents in a 1:2 individual matching. Through the questionnaire survey to obtain the general situation of the research, the occupation history, the diet custom, the diet content, the digestive tract disease history, family cancer history, the psychological factor and so on.2采用检验对研究对象的婚姻状况、文化程度、职业等一般人口学资料的分布差异进行比较；用Cox回归分析计算相对危险估计值（胜算比，或值）、P值和或值的95%可信区间；Cox采用多因素回归分析筛选胃癌发生主要危险因素；根据布鲁奇推荐的公式计算人群归因危险度。
结果仙游县胃癌的可能危险因素主要有：饮食速度快、喜食干硬食物、高盐饮食、饭后劳作、吃腌菜；可能的保护因素主要有
牛羊肉、海带紫菜、洋葱、蔬菜、食用菌。Conclusion the incidence of gastric cancer in Xianyou county is related to a variety of dietary factors, and some positive measures should be taken to improve the eating habits of people in Xianyou county to reduce the incidence of gastric cancer. Key words: gastric cancer: a case control study