We report biodegradable plasmon resonant
liposome gold nanoparticles (LiposAu NPs) capable of killing
cancer cells through photothermal therapy. The pharmacokinetic
study of LiposAu NPs performed in a small animal model
indicates in situ degradation in hepatocytes and further getting
cleared through the hepato-biliary and renal route. Further, the
therapeutic potential of LiposAu NPs tested in mouse tumor
xenograft model using NIR laser (750 nm) illumination
resulted in complete ablation of the tumor mass, thus
prolonging disease-free survival