To provide energy for the metabolism of the organism and to provide a precursor for the synthesis of amino acids. According to the coenzyme specificity, IDH can be divided into two categories, NAD- dependent IDH (EC1.1.1.41, NAD-IDH) and NADP- dependent IDH (EC1.1.1.42, NADP-IDH). NADP-IDH can be divided into two forms, two forms of the same type and single type. Most eukaryotes and prokaryotes contain two homologous dimers NADP-IDH, a bacterium containing monomer NADP-IDH. NAD-IDH has two kinds of existing forms of two kinds of different forms of the same source of the dimer and the heterologous. Eukaryotic NAD-IDH is a heterogeneous polymer,Some bacteria and the NAD-IDH of the ancient bacteria were homologous to the two.
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