Exercise may additionally produce neuroprotective
benefits through other multi-faceted mechanisms.
Another possible mechanism, further oxidative stress or
immune, that modulated the neuroprotective exercise in a PD model induced by 6-OHDA in mice can be the
decrease in the expression of the dopamine transporter
(DAT), D2, adenosine, NR2A and NR2B receptors on
nigrostriatal cells and their terminal.