Student's t-test or analysis of variance (ANOVA) was used to compare the values of the test and control samples in vitro and in vivo. The associations between YB-1 or MACC1 expression and categorical variables were compared by Pearson chi-square test. Survival curves were calculated using the Kaplan Meier method. The log-rank test was used to analyze overall survival (OS) time between different clinicopathological factors in lung adenocarcinoma. Multivariate analysis was performed using the Cox regression model. Data was analyzed by the SPSS 20 software (Inc, Chicago, IL). Values of p