Gijsbers et al. conducted a double-

Gijsbers et al. conducted a double-blinded placebo-
controlled (DBPC) trial in children with recurrent abdom-
inal pain. First, 121 children performed a HBT with 2 g/kg
fructose (max. 50 g). From those children who were posi-
tive (65 %), 49 were set on a fructose elimination diet.
Sixty-five percent of them reported absence of symptoms
during the diet but only 13 out of 31 children (41 %)
responded to an open provocation with fructose. Finally, all
8 children which demonstrated symptoms after provoca-
tion, showed no symptoms after double-blinded placebo-
controlled re-provocation. In summary, none of the chil-
dren demonstrated positive hydrogen breath test together
with the absence of symptoms during elimination and
symptoms during the DBPC trial. An explanation why the
children showed positive hydrogen breath test after
fructose ingestion but no symptoms during DBPC with
fructose could be the different dose. During the breath
test, a maximum of 50 g fructose (2 g/kg) was given
whereas in the DBPC trial, 25 g was consumed over the whole day. However, factors such as the gut microbiota,
transit time and diet composition might also cause varying
fructose tolerance [23]. As mentioned above, 2 g/kg fruc-
tose cannot be completely absorbed in the majority of
children. Therefore, the dose is too high to discriminate
between fructose absorption and malabsorption. Since the
elimination and provocation was conducted at home, it is
possible that children did not strictly follow the elimin-
ation and provocation guidelines leading to inconsistent
results. Nevertheless, fructose malabsorption was most
likely not the prominent factor for abdominal pain in this
cohort.

結果 (中文) 1:

Gijsbers 等人进行了双盲安慰剂小儿复发性 abdom-对照 (DBPC) 试验inal 疼痛。首先，121 儿童执行 HBT 与 2g/kg果糖 （最多 50 克）。从这些孩子们岗位-敏感 （65%)，49，设置对果糖消除饮食。65%的人报告说没有症状期间的饮食，但只有 13 个 31 儿童 （41%)回应与果糖的公然挑衅。最后，所有8 个孩子之后并带有挑逗性-, 表现症状化后双盲安慰剂, 表现出任何症状控制稀土挑衅。总之，没有任何的部族儿童一起显示积极氢呼气试验在消除症状的情况下，DBPC 审判期间的症状。解释为什么孩子们展示积极的氢呼气试验后但没有症状期间与 DBPC 的果糖摄入果糖可能是不同的剂量。在呼吸时测试，给出了最多的 50 克果糖 (2 g/kg)而在 DBPC 试验中，在整个一天消耗 25 克。然而，对肠道菌群等因素过境时间和饮食成分也可能导致不同的果糖容忍 [23]。如上所述，2 g/kg 处方中-东星不能完全吸收大部分的儿童。因此，剂量是太高了，歧视果糖的吸收与吸收不良。因为在家里进行了消除和挑衅，它是可能，孩子没有严格遵循翳-导致不一致的信息和挑衅行为准则结果。然而，果糖吸收不良是大多数可能不是突出因素为腹痛在这的队列。

結果 (中文) 3:

gijsbers等。进行了双blinded安慰剂控制（dbpc）Trial in children with性腹腔-创新的面包。第一，121儿童执行了HBT以及2克/公斤果糖（最大。50克）。从这些儿童谁是熟悉的遮阳（65%），49 were set我们果糖消除饮食。六十五percent of them reported缺乏症状during the饮食，但是只有13 out of 31 children（41%）responded to an open挑衅以及果糖。最后，所有的儿童表现出症状后，8 provoca -化，表明没有症状后双blinded安慰剂控制再挑衅。in summary，none of the旗孩子们表现出积极的氢呼吸试验在一起with the absence of symptoms在消除and症状during the dbpc试验。年解释为什么儿童正氢呼吸试验后给果糖摄入的目标没有症状在dbpc with果糖could be the不同剂量。during the呼吸测试，最高可达50克果糖（2克/公斤）was given而在dbpc Trial，25克是consumed over the whole day。然而，因子such as the好microbiota，运输时间和饮食成分可能也变的原因果糖耐受[ 23 ]。你上面提到的，2克/公斤FRUC -东星cannot be completely吸收in the majority of儿童。因此，剂量太高discriminate is to之间的吸收和果糖吸收不良。since the消除和挑衅was conducted at home，it is可能那孩子did not strictly follow the消除-信息和挑衅Guidelines leading to不一致结果。然而，果糖吸收不良was mostlikely not the普罗名特因子for腹痛in this队列。