323. Radiother Oncol. 2001 Mar;58(3):313-6.
Comparison of three rat strains for development of radiation-induced lung injury
after hemithoracic irradiation.
van Eerde MR(1), Kampinga HH, Szabo BG, Vujaskovic Z.
Author information:
(1)Department of Radiotherapy, University Hospital Groningen, Hanzeplein 1, 9700
RB Groningen, The Netherlands.
The purpose of this study is to define differences in radiation sensitivity among
rat strains using breathing frequency and lung perfusion as end points of
radiation-induced lung injury. The results have confirmed previous findings in
mice showing that under stringently controlled iso-dose/volume irradiation
conditions, substantial differences can be found in susceptibility to functional
lung damage after radiation.
PMID: 11230893 [PubMed - indexed for MEDLINE]